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Common Names for Hypochlorous Acid Solutions


  • Electrolytically Generated Hypochlorous Acid
  • Neutral Electrolyzed Water (NEW)
  • Electrolyzed Oxidizing Water (EOW)
  • Electro-chemically Activated Water (ECA)
  • Super-oxidized water (SOW)


Results: 2 published articles


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Microbe(s): Bacillus spores, Candida, Acinetobacter, Shigella, Serratia, Proteus, Pseudomonas, Mycobacterium tuberculosis, Mycobacterium avium, Mycobacterium abscessus, MRSA, VRSE


Background : Disinfection is essential for the prevention of hospital infection. Medilox, an super oxidized water generated by Medilox (SOO SAN EC CO., LTD. Yongin, Korea) was developed as a disinfectant in Korea. This is not costly and does not caany clinical problems and environmental pollution. We evaluated bactericidal activity ofMedilox against several clinical isolates and standard strains. Method : Clinical isolates and reference ATCC strains were exposed to Medilox, an super oxidized water (80 ppm ofHOCl) generated by Medilox (SOO SAN ECCO., LTD. Yongin, Korea) for the various periods (0.5, 1, 2, 5, and 10 minutes). After the exposure mixture of microorganisms and Medilox solution was inoculated into tryptic soy broth and onto tryptic soy agar, Sabouraud dextrose agar or Ogawa medium and cultured at 35C. Results: All strains of bacteria, yeasts, mycobacteria and vegetative form of Bacillus subtilis were killed within 30 seconds after an exposure to Medilox (80 ppm ofHOCl) under clean and dirty conditions. But, spore form of Bacillus subtilis was killed within 5 minutes. Conclusion: It may be recommended that Medilox can be used for the effective disinfectant for hospital environments and high-level disinfectant for hospital infection control.



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Microbe(s): Enterococcus faecium, Mycobacterium avium subspecies avium, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans


Standards of the German Association of Veterinary Medicine (DVG) for the evaluation of chemical disinfectants were used to assess the anti-microbial efficacy of electrolysed oxidizing water (EOW). Enterococcus faecium, Mycobacterium avium subspecies avium, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus and Candida albicans were exposed to anode EOW (pH, 3.0 0.1; oxidation-reduction potential (ORP), +1100 50 mV; free chlorine, 400 20 mg/l Cl2) and combined EOW (7 : 3 anode : cathode, v/v; pH, 8.3 0.1; ORP, 930 950 mV; free chlorine, 271 20 mg/l Cl2). In water of standardized hardness (WSH), all bacterial strains were completely inactivated by a 30 min exposure to maximum 10.0% anode EOW ( 40.0 mg/l Cl2) or 50.0% combined EOW ( 135.5 mg/l Cl2). The sensitivity ranking order for anode EOW to the bacterial test strains was P. mirabilis > S. aureus > M. avium ssp. avium > E. faecium > P. aeruginosa. P. mirabilis and S. aureus decreased to undetectable levels after 5 min of exposure to 7.5% anode EOW ( 30.0 mg/l Cl2). Candida albicans was completely inactivated by a 5-min exposure to 5.0% anode EOW. Both, anode and combined EOW exhibited no anti-microbial activities in standardized nutrient broth or after addition of 20.0% bovine serum to the WSH. Further research is necessary to evaluate the efficacy of EOW as a disinfectant under operating conditions in animal production facilities.